Pulsatile Insulin Delivery Through the Ocular Route
نویسندگان
چکیده
منابع مشابه
Pulsatile insulin secretion dictates systemic insulin delivery by regulating hepatic insulin extraction in humans.
In health, insulin is secreted in discrete pulses into the portal vein, and the regulation of the rate of insulin secretion is accomplished by modulation of insulin pulse mass. Several lines of evidence suggest that the pattern of insulin delivery by the pancreas determines hepatic insulin clearance. In previous large animal studies, the amplitude of insulin pulses was related to the extent of ...
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ژورنال
عنوان ژورنال: Drug Delivery
سال: 1998
ISSN: 1071-7544,1521-0464
DOI: 10.3109/10717549809052026